Cardiac output is the product of heart rate and stroke volume. Cardiac output is "monitored" by the autonomic nervous system via the mean arterial blood pressure. Changes in the mean arterial blood pressure influence the information coming from the autonomic nervous system, and thus have an effect on the heart rate and contraction dynamics of the myocardium, resulting in the adaptation of the cardiac output to current metabolic demand.
In patients with chronotropic incompetence or other dysfunctions of the sinus node, CLS monitors the contraction dynamics and translates them into proper heart rate adaptation, thus delivering proven physiological therapy.
By clicking the links below to access the news on our International website, you are leaving this website. In case of sinus node dysfunction , the heart rate cannot be changed by the ANS.
However, the ANS can increase the stroke volume by acting on myocardium contractility, but a high stroke volume is deterious for the patient. The CLS sensor measures the contraction dynamics of the myocardium and translates them into proper heart rate adaptation, thus delivering proven physiological therapy.
CLS is really easy to use for physicians. The impedance is measured at the tip of the right ventricular lead and it reflects changes seen during systole. At the beginning of the systole, blood and muscle volume define the impedance value 1.
When the contraction starts, the percentage of muscle volume will increase, resulting in a higher impedance value 2 3 4. Janine, a year-old teacher, was diagnosed with vasovagal syncope. By clicking the links below to access the news on our International website, you are leaving this website. Closed Loop Stimulation. From Vision to Impact One Life. Take Control with CLS.
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