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All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Mayo Clinic does not endorse companies or products. If you still have symptoms of infection after you finish the chloramphenicol injection, talk to your doctor. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.
You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. Generic alternatives may be available. Chloramphenicol Injection pronounced as klor am fen' i kol. Why is this medication prescribed? How should this medicine be used?
Other uses for this medicine What special precautions should I follow? What special dietary instructions should I follow? What side effects can this medication cause? Brand names. Talk to your doctor about the risks of receiving chloramphenicol injection. Other uses for this medicine. What special precautions should I follow? Before receiving chloramphenicol injection, tell your doctor and pharmacist if you are allergic to chloramphenicol injection or any other medications.
Be sure to mention any of the following: anticoagulants ''blood thinners'' such as warfarin Coumadin ; aztreonam Azactam ; cephalosporin antibiotics such as cefoperazone Cefobid , cefotaxime Claforan , ceftazidime Fortaz, Tazicef , and ceftriaxone Rocephin ; cyanocobalamin vitamin B 12 ; folic acid; iron supplements; certain oral medications for diabetes such as chlorpropamide Diabinese and tolbutamide; phenobarbital; phenytoin Dilantin, Phenytek ; rifampin Rimactane, Rifadin ; and medications that may cause a decrease in the number of blood cells in the body.
Ask your doctor or pharmacist if any of the medications that you are taking may cause a decrease in the number of blood cells.
Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Other medications may also interact with chloramphenicol injection, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may tell you not to use chloramphenicol injection.
If you're affected, it's best not to drive or ride a bike until you feel back to normal. Page last reviewed: 6 December Next review due: 6 December Chloramphenicol On this page About chloramphenicol Key facts Who can and cannot take chloramphenicol How and when to use chloramphenicol Side effects Pregnancy and breastfeeding Cautions with other medicines Common questions.
About chloramphenicol Chloramphenicol is an antibiotic. It also comes as ear drops. These are on prescription only.
Help us improve our website Can you answer a quick question about your visit today? Chloramphenicol is safe for most adults and children. For most eye infections, you'll usually start to see an improvement within 2 days of using chloramphenicol.
For ear infections, you should begin to feel better after a few days. Your eyes may sting for a short time after using the eye drops or ointment. The ear drops may cause some mild discomfort. Chloramphenicol can be used by most adults and children. To make sure chloramphenicol is safe for you, tell your doctor if you have: had an allergic reaction to chloramphenicol or any other medicines a rare illness called aplastic anaemia when your bone marrow doesn't produce blood cells Eye drops or ointment Before using chloramphenicol, tell you doctor if you're using other eye drops or ointment, or if you normally wear contact lenses.
It's also important to speak to your doctor if you have: any problems with your eyesight, or severe eye pain swollen eyes, and a rash on your face or head a cloudy eye unusual looking pupils - irregular size, dilated bigger than normal , or not reacting to light had a recent eye injury, or something in your eye recently had conjunctivitis dry eye syndrome when your eyes don't produce enough tears glaucoma had eye surgery or laser treatment in the last 6 months Ear drops Before using chloramphenicol ear drops, tell your doctor if you: have a perforated burst eardrum are allergic to polyethylene glycol an ingredient used in some medicines and cosmetics, and found in some foods.
To use the medicine: always wash your hands before and after using chloramphenicol - this prevents you from passing the infection to the other eye or ear remove the cap just before using your medicine and replace it as soon as you've finished do not touch the nozzle of the bottle or tube with your fingers make sure the nozzle doesn't touch your eye or ear, or your skin use a mirror to help you see what you are doing tilt your head back or to the side to put drops in your eyes or ears How to apply eye drops Gently pull down your lower eyelid with a clean finger and tilt your head back.
How to apply eye ointment Gently pull down your lower eyelid with a clean finger and tilt your head back. How to apply ear drops Tilt your head and bring the tube up to the affected ear, with the nozzle close to your ear hole. How long to use it for Eye drops - use the drops until the eye appears normal and for 2 days afterwards. What if I forget to take it? What if I take too much? Common side effects These common side effects happen in more than 1 in people.
Serious side effects Serious side effects are rare and happen in less than 1 in 1, people. Call a doctor straight away if you: bruise more easily get infections more easily feel especially tired or weak These can be signs of aplastic anaemia, a rare condition where your bone marrow fails to produce blood cells normally. Serious allergic reaction In rare cases, it's possible to have a serious allergic reaction anaphylaxis to chloramphenicol.
Information: You can report any suspected side effect using the Yellow Card safety scheme. Visit Yellow Card for further information. Chloramphenicol and breastfeeding Avoid using chloramphenicol if you're breastfeeding, especially if your baby was born prematurely, or if there's a family history of any sort of blood disorder, including aplastic anaemia. Talk to your doctor about what's right for you and your baby.
Non-urgent advice: Tell your doctor if you're:. There are some medicines that don't mix well with chloramphenicol. Tell your doctor if you're taking or have recently taken these medicines before you start using chloramphenicol: medicines for cancer medicines for the immune system such as azathioprine prescribed for rheumatoid arthritis, Crohn's disease, ulcerative colitis, or if you've had a kidney transplant Mixing chloramphenicol with herbal remedies and supplements There are no known problems with taking herbal remedies and supplements alongside chloramphenicol.
Important: Medicine safety Tell your doctor or pharmacist if you're taking any other medicines, including herbal medicines, vitamins or supplements. How does chloramphenicol work? Can I use chloramphenicol if I wear contact lenses? What's the difference between using chloramphenicol eye drops and ointment?
Are prescription chloramphenicol eye drops different to the ones you can buy? When will I feel better? For most eye infections, you should notice an improvement within 2 days. For ear infections, you'll notice improvement within a few days. What if I don't get better? Will it affect my contraception? Will it reduce my fertility? Will it give me thrush? Can I drink alcohol with it? Yes, you can drink alcohol with chloramphenicol. Is there any food or drink I need to avoid?
Can I drive or ride a bike? Chloramphenicol shouldn't affect you being able to drive or cycle. Related conditions Conjunctivitis Ear infections.
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